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Description

Opioid-induced hyperalgesia is a paradoxical increase in pain sensitivity caused by repeated opioid exposure

Outpatient treatment of propionic acidemia-associated hyperammonemia with N-carbamoyl-L-glutamate in an infant

Two complementary paths are promising: (1) established postbiotic formulations - purified, chemically characterized metabolites, or metabolite mixtures that are formulated for topical or local use (gels, mouth rinses, vaginal suppositories, device coatings)